Florence is full of wonderful stores and boutiques in historic locations and buildings, but some of the businesses themselves are also historic. One of them is Farmacia Santissima (“SS”) Annunziata dal 1561, an Italian apothecary and perfumery that dates back to the 16th century. The perfumery creates its own fragrances as well as cosmetics and lotions. It has its own page on Fragrantica, with 33 perfumes listed there. I was able to visit the actual store a few weeks ago, on a long-awaited first trip to Florence, and it was well worth it! I discovered its existence thanks to a wonderful article by The Perfume Society about perfume-shopping in Florence.
The Farmacia is right around the corner from Florence’s Galleria dell’Accademia, home of Michelangelo’s David, which we were able to see early in the morning, at the first opening of the museum. We were the first visitors into the gallery that day, which was an unforgettable experience — looking down the whole length of the beautiful gallery at that magnificent statue, without anyone else in sight, then slowly approaching it and realizing just how tall David is. It reminded me, in reverse, of how much smaller the painted Mona Lisa looks in real life than how one imagined.
The store itself is charming and beautiful. It is paneled on every wall with floor-to-ceiling cabinets full of bottles and jars, and it has a gorgeous long counter across almost the full length of the back. The staff are friendly, knowledgeable, and fluent in English. Honestly, just visiting the store was a treat in itself. But of course, I couldn’t resist trying several of the fragrances!

Bottles of products at Farmacia SS Annunziata dal 1561
One I particularly liked is Regina, an eau de toilette with notes of rose, unnamed “floral notes”, ylang-ylang, honey, rice, amber, iris, and chamomile. The most prominent notes are iris, rice, and honey, but ylang-ylang and chamomile are noticeable also. The strongest impression I get from it on my skin is that of a lovely, flowery powder. It is soft and honeyed without being sugary. The iris note is based, of course, on Florentine iris, a traditional and costly source of the prized orris butter that goes into many fragrances; its preeminence in Regina is a beautiful remembrance of lovely Florence.
I don’t really smell rose in isolation from the other notes; in fact, when I first spray Regina, I smell iris right away. But it is an iris supported by other flowers, so I’m sure the rose is there! The ylang-ylang adds a polleny yellow flower aspect to the scent, which enhances the notes of rice and honey, lending Regina a golden tone that is both light and warm.
This is an unusual combination of notes, especially with the chamomile that is so rarely used today in fragrances. One exception is the much commented-on recent release from Gucci, Memoire d’Une Odeur, which I tried the other day and liked very much; there has been a lot of online chatter about Alberto Morillas’ use of chamomile in that fragrance. I love green and herbal notes in fragrance, so chamomile appeals to me (and I like chamomile tea, so I’m predisposed to like it as a scent). Regina feels quite linear to my nose, which I don’t mind at all because it is such a pretty, appealing scent.
When we visited Florence and the Farmacia, Italy was suffering from the same heat wave that affected all of Europe in late July. Upon our return, the weather here at home has been almost as hot, and twice as humid. Regina is an ideal summer fragrance, with its light touch and notes of summery blossoms. It has a base note of amber, but this amber is delicate and does not overwhelm or overpower the rice, powder, and summer flowers. I often turn to one of Hermes’ Jardin fragrances in this kind of heat, or Penhaligon’s Blasted Bloom, as they both have a cooling, refreshing effect, but Regina will join my regular summer rotation.
Blogger Kafkaesque has written about Farmacia SS. Annunziata, noting the quality and reasonable prices of its fragrances. Have you tried any of them? If you were to choose a fragrance for a hot summer day in Florence, what would you choose?
I have not tried any of them and wonder now if the shop was there in 1994 as I was in the gallery to see Michaelangelo’s David.
A hot summer day in Florence fragrance? Maybe Orange Sanguine?
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It’s so fun to hear about your trip to Florence!
That’s so nice that you got to visit Farmacia and smell some goodies. I sampled Farmacia Isos from Luckyscent years ago. It’s a cool spiced blackpepper composition. I’m not sure if Isos is still in production. I don’t see it on Luckyscent anymore. I had been thinking about possibly sampling Regina, so it’s great to hear your thoughts on it!
Yes, chamomile seems trendy at the moment due to Memoire d’une Odeur!
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I really like Regina a lot! They do still make Isos, but I didn’t try it. Next time!
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